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Later, several other GLP-1 receptor agonists have been approved (liraglutide, albiglutide, lixisenatide, dulaglutide and semaglutide) (24)

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In clinical trials for weight management (SURMOUNT-1), participants without diabetes lost approximately 15% of body weight at 5 mg, 20% at 10 mg, and 21% at 15 mg over 72 weeks